Circular Dichroism (CD) spectrometry is used for secondary structure analysis of proteins (and other molecules which are chiral in structure).
For example the content of helix, b-sheet, random structure etc. can be determined within a protein. This technique is useful for measuring systems which undergo structural change such as the unfolding of proteins or helix formation in the presence of lipid etc. It is also a useful measure of determining if your protein is properly folded before entering other experiments such as NMR.
Please contact us on info@proteomics.com.au for more information.