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Prognostic value of a plasma protein-based biomarker test for chronic kidney disease complicating diabetes in Aboriginal Australians

Timothy M. E. Davis,1,2,3 Kirsten E. Peters,4 Scott Bringans,4 Daniel McAullay,5 Arvind Singh,4Richard J. Lipscombe4 and Wendy A. Davis1,3

Abstract

The predictive value of Promarker®D tests for incident diabetic kidney disease or rapid decline in estimated glomerular filtration rate was evaluated in 1010 non-Aboriginal and 71 Aboriginal adults with diabetes. Areas under the receiver operating characteristic curves were not significantly different (P ≥ 0.081) for first- (non-Aboriginals 0.890 (95% confidence interval 0.864 to 0.915) and Aboriginals 0.769 (0.624 to 0.915)) and second-generation (0.890 (0.862 to 0.917) and 0.711 (0.543 to 0.878)) tests. Promarker®D has potential renal prognostic value in Aboriginals with diabetes.

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